Abstract #5044

Diffusion kurtosis and elastography of uncinate fasciculus relate to dysfunctional emotion regulation and anxiety in youth

Melanie A Matyi¹, Leah D Church¹, Jeremy S Rudoler¹, Nadia Bounoua¹, Kaleigh E Wieand¹, Grace McIlvain², Curtis L Johnson², and Jeffrey M Spielberg¹

¹Psychological and Brain Sciences, University of Delaware, Newark, DE, United States, ²Biomedical Engineering, University of Delaware, Newark, DE, United States

Synopsis

Keywords: Psychiatric Disorders, Adolescents, anxietyMechanistic theories seeking to explain the onset of anxiety in adolescence propose that delayed myelination of the uncinate fasciculus (UF) confers risk for anxiety onset through, in part, deficits in regulation of emotions. Thus, we examined the relationship between two independent assays of UF structural integrity and measures of both dysfunctional emotion regulation and anxiety. We found that less UF structural integrity is related to more dysfunctional emotion regulation and anxiety. Furthermore, we found that dysfunctional emotion regulation mediates the relationship between UF structural integrity and anxiety.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.