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Abstract #5054

Functional and structural brain alterations in autism spectrum disorder: A multimodal meta-analysis of neuroimaging studies

Zixuan Guo1, Hong Yan1, Xinyue Tang1, long Qian2, and Ying Wang1
1Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, China, 2MR Research, GE Healthcare, Beijing, China

Synopsis

Keywords: Psychiatric Disorders, Brain, fMRI(resting state); Grey matter volumeNumerous neuroimaging studies conducted have shown functional and structural brain alterations in patients with ASD. We conducted a whole-brain voxel-wise meta-analysis to summarize previous inconsistent results by using Seed-based d Mapping software. In the present multimodal meta-analysis, functional and structural alterations in specific regions were found, which provide new insights into the quest for a neuroimaging-based marker for ASD.

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