Abstract #5099

Blood Oxygen Level-Dependent Imaging in Peripheral Artery Disease: Feasibility and Reproducibility of perfusion measurements

Xiaoxi Yu¹, Zhaoxi Liu², Jianxun Qu³, Fengdan Wang², Zhichao Lai¹, Xiaoyuan Fan², Luming Ye⁴, Jiang Shao¹, Yan Zhang², Bao Liu¹, Zhengyu Jin², and Feng Feng²

¹Vascular Surgery, Peking Union Medical College Hospital, Beijing, China, ²Radiology, Peking Union Medical College Hospital, Beijing, China, ³MR Collaboration, Siemens Healthineers Ltd., Beijing, China, ⁴Advanced Therapies Collaboration, Siemens Healthineers Ltd., Beijing, China

Synopsis

Keywords: Quantitative Imaging, PerfusionThis study used blood oxygen level-dependent (BOLD) imaging to assess the hemodynamics of the lower limbs among elder controls and patients with peripheral artery disease (PAD). The BOLD-derived perfusion parameters, such as time to peak and gradient during reactive hyperemia, showed good reproducibility and significantly differed between patients and controls. The results indicated decreased vasodilatation ability and perfusion levels in patients with PAD. Therefore, BOLD imaging can be a feasible perfusion assessment method for long-term noninvasive PAD monitoring.

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