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Abstract #5100

7T cross-vendor repeatability study of cartilage T2 values using DOSMA on qDESS images

Jessica Lauren Asay1, Krithika Balaji2, Anthony A Gatti1, Arjun D Desai1, Michael Mendoza2, Zimu Huo2, Akshay S Chaudhari1,3, Feliks Kogan1, Peter J Lally4,5, Neal K Bangerter2, and Garry E Gold1
1Radiology, Stanford University, Stanford, CA, United States, 2Bioengineering, Imperial College London, London, United Kingdom, 3Biomedical Data Science, Stanford University, Stanford, CA, United States, 4Brain Sciences, Imperial College London, London, United Kingdom, 5UK Dementia Research Institute Centre for Care Research and Technology, London, United Kingdom

Synopsis

Keywords: Quantitative Imaging, Data Processing, Repeatability, cartilage, knee

Cartilage T2 relaxation times (T2), used to detect early knee osteoarthritis, lack standardization in acquiring and processing data, making comparisons between studies difficult. Standardizing image post-processing could possibly control for biases. Here, we assess qDESS cartilage T2 repeatability across two different sites and 7T scanner vendors with identical automatic segmentation and T2 mapping software. Within-site repeatability was good (ICC≥ 0.75) for most cartilage regions, while cross-vendor repeatability was good for the tibial and femoral posterior cartilage. This preliminary study shows standardizing acquisition and post-processing can lead to repeatable T2 values across different vendors.

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Keywords