Abstract #5107

Low-Rank Plus Sparse Accelerated Proton Resonance Frequency Shift and T1-mapping with a Dual-Echo 3D Spiral Ultra-Short Echo Time Sequence

Sheng Chen¹, Zhixing Wang¹, Yekaterina K. Gilbo², Helen L. Sporkin¹, Samuel W. Fielden³, Steven P. Allen⁴, John P. Mugler III⁵, G. Wilson Miller⁵, and Craig H. Meyer^1,5

¹Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, ²Netflix, Los Gatos, CA, United States, ³U.S. Food and Drug Administration, Silver Spring, MD, United States, ⁴Brigham Young University, Provo, UT, United States, ⁵Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States

Synopsis

Keywords: Sparse & Low-Rank Models, Image Reconstruction, UTE, Spiral, Focused Ultrasound

Unintended heating of the skull and nearby brain tissue during MR-guided Focused Ultrasound (MRgFUS) treatment is not standardly monitored. A method for addressing this issue, which combines variable flip angle (VFA) T1 mapping and proton resonance frequency (PRF) shift thermometry based on a dual-echo 3D spiral ultra-short echo time (UTE) acquisition, was accelerated with a low-rank plus sparse model in image reconstruction and validated using retrospectively undersampled data in vitro.

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