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Abstract #5113

Quantitative Ultrashort Echo-Time MRI to Assess In Vivo Rotator Cuff Tendon Degeneration

Misung Han1, Peder EZ Larson1,2, Thomas M Link1, Drew A Lansdown3, Brian T Feeley3, and Sharmila Majumdar1,2
1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2UCSF-UC Berkely Graduate Program in Bioengineering, University of California, San Francisco, San Francisco, CA, United States, 3Department of Orthopaedic Surgery, San Francisco, CA, United States

Synopsis

Keywords: Tendon/Ligament, Quantitative ImagingRotator cuff tears are a common source of pain and disability. Surgical treatment is normally considered for patients who fail in non-operative management, but a failure of tendon healing after surgery can be dependent on tendon quality. In this work, we applied two ultrashort-echo time (UTE) quantification imaging methods, UTE T2* quantification as well as UTE magnetization transfer (MT) quantification, on healthy subjects and patients with rotator cuff tears, and evaluated their ability to assess tendon degeneration. Significant difference was observed for quantified T2* and MT parameters over segmented supraspinatus tendon between the healthy control and patient groups.

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