Keywords: Skeletal, Magnetization transfer, Intervertebral discQuantitative ultrashort echo time (UTE) MRI can be used for quantitative assessment of intervertebral discs (IVDs). It is hypothesized that the investigation of quantitative UTE MRI properties of IVD under mechanical loading may highlight the affected regions of IVD by diseases and injuries. We investigated the feasibility of using UTE-T1, UTE-Adiab-T1ρ, and UTE-MT measures for detecting the IVD deformation under loading. T1 and T1 ρ decreased in IVDs under loading while MMF from UTE-MT modeling as an index for collagen content increased by loading. This study highlights the potential of UTE-MRI to detect subvoxel deformations in IVDs caused by loading.
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