Keywords: Elastography, In SilicoSimulations can play an important role in validating the accuracy of MR elastography (MRE) inversion algorithms. A realistic brain MRE simulation is created through a finite element model from in vivo MRE data, with 20 randomly generated simulated brains created by assigning properties of anatomical segmentations of brain structures within a range given by a published MRE atlas. Multi-frequency and multi-direction synthetic MRE data was generated via boundary conditions from in vivo measured motions to allow a range of inversion algorithms to be tested. These data will be supplied to the MRE study group for an inversion reconstruction challenge.
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