Abstract #5150

Transversely Isotropic MR Elastography with a Power Law Multi-Frequency Reconstruction

Diego A. Caban-Rivera¹, Elijah E. W. Van Houten², Matthew D. J. McGarry³, L. Tyler Williams¹, Phil V. Bayly⁴, Keith D. Paulsen³, and Curtis L. Johnson¹

¹Biomedical Engineering, University of Delaware, Newark, DE, United States, ²Département de Génie Mécanique, Université de Sherbrooke, Sherbrooke, QC, Canada, ³Thayer School of Engineering, Dartmouth College, Hanover, NH, United States, ⁴McKelvey School of Engineering, Washington University in St. Louis, St. Louis, MO, United States

Synopsis

Keywords: Elastography, Brain

This study combined multiexcitation MRE (ME-MRE), and multifrequency MRE (MF-MRE) with a transversely isotropic nonlinear inversion (TINLI) and axonal fiber directions from diffusion tensor imaging to investigate anisotropic and frequency-dependent material properties simultaneously. These preliminary results show that multifrequency-TINLI MRE can be readily applied to in vivo human data at distinct frequencies.

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