Abstract #5155

Mesenteric Adipose Tissue in Crohn’s Disease assessed by in vivo MR Elastography

Rolf Reiter¹, Florian Nino Loch², Carsten Kamphues³, Mehrgan Shahryari¹, Stephan Rodrigo Marticorena Garcia¹, Britta Siegmund⁴, Carl Weidinger⁴, Anja Kühl⁵, Bernd Hamm¹, Jürgen Braun⁶, Ingolf Sack¹, Patrick Asbach¹, and Laura Jensen¹

¹Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ²Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany, ³Surgery, Parkklinik Weißensee, Berlin, Germany, ⁴Gastroenterology, Infectious Diseases and Rheumatology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁵iPATH.Berlin-Immunopathology for Experimental Models, Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁶Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

Synopsis

Keywords: Elastography, Body, inflammatory bowel disease

Despite increasing evidence that the functional involvement and structural changes of mesenteric adipose tissue influence the course of Crohn's disease, its viscoelastic properties remain elusive. We demonstrate the feasibility of in vivo MR elastography of mesenteric adipose tissue and present preliminary reference values for Crohn's disease patients and healthy controls in this explorative study. Our preliminary results show an excellent diagnostic performance in detecting Crohn's disease by assessing the viscoelastic properties of mesenteric adipose tissue using histopathology of surgical specimens as reference. Our results motivate further studies for the biophysical characterization of mesenteric adipose tissue in inflammatory bowel disease.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.