Abstract #5156
Intrinsic MR elastography for classification of focal liver lesions using normalized viscoelastic parameters: a pilot study
Amirhosein Baradaran Najar1,2, Elige Karam2,3, Guillaume Gilbert4, Maxime Barat2,3, Emmanuel Montagnon3, Hélène Castel5, Jeanne-Marie Giard5, Bich Nguyen6, Guy Cloutier2,7,8, An Tang2,7, and Elijah Van Houten1,9
1Département du génie mécanique, Université de Sherbrooke, Sherbrooke, QC, Canada, 2Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada, 3Department of Radiology, Radiation Oncology and Nuclear Medicine, Université de Montréal, Montréal, QC, Canada, 4Philips Healthcare, Mississauga, ON, Canada, 5Centre Hospitalier de l’Université de Montréal (CHUM), Montréal, QC, Canada, 6Service of Pathology, Centre Hospitalier de l’Université de Montréal (CHUM), Montréal, QC, Canada, 7Institute of Biomedical Engineering, Université de Montréal, Montréal, QC, Canada, 8Laboratory of Biorheology and Medical Ultrasonics(LBUM), Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montréal, QC, Canada, 9Centre de recherche du Centre hospitalier de l'Université de Sherbrooke (CRCHUS), Sherbrooke, QC, Canada
Synopsis
Keywords: Elastography, Elastography, Intrinsic magnetic resonance elastography, CancerIntrinsic activation MR elastography (iMRE) method has been applied to a cohort of patients undergoing liver MRI for assessment of focal liver lesions. We used segmentation, masking, and normalization of viscoelastic parameters to investigate the capability of this method to differentiate benign and malignant liver lesions. The normalized storage modulus (G') computed by nonlinear inversion-iMRE showed significant differences between benign and malignant lesions.
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