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Abstract #5189

8-minute Rapid Whole-brain Diffusion Spectral Imaging with Deep Learning-based Reconstruction: A Feasibility Study

Yuhui Xiong1, Xiaocheng Wei1, Jiankun Dai1, Yang Fan1, Jie Lu2, and Bing Wu1
1GE Healthcare MR Research, Beijing, China, 2Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Machine Learning/Artificial Intelligence

This study aims to shorten the diffusion spectral imaging (DSI) scan time to a clinically acceptable level while providing satisfactory complex white matter fiber structure description as well as accurate diffusion metric quantification by applying deep learning-based reconstruction. Images were acquired using conventional (≈30 min) and rapid (≈8 min) DSI sequences, and reconstructed using conventional and DL-based methods, respectively. Atlas-based fiber-tracking and diffusion metrics quantification from various advanced models were conducted. The results demonstrated that the 8-minute rapid DSI sequence combined with DL-recon can provide complex fiber structure tractography and advanced diffusion metric quantification of satisfactory quality.

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Keywords