Abstract #5201
Quantification of Lesion Volume Differences in Structural Epilepsy in 7T and 3T
Stefanie Chambers1,2, Lukas Haider3, Philipp Lazen1, Gregor Kasprian3, Johannes Koren4, Robert Diehm5, Katharina Moser5, Matthias Tomschik1, Jonathan Wais1, Fabian Winter1, Vitalij Zeiser1, Stephan Gruber2,6, Susanne Aull-Watschinger7, Tatjana Traub-Weidinger8, Christoph Baumgartner 4, Martha Feucht5, Christian Dorfer1, Wolfgang Bogner2,6, Siegfried Trattnig2,6, Ekaterina Pataraia7, Karl Rössler1,6, and Gilbert Hangel1,2,6
1Department of Neurosurgery, Medical University of Vienna, Vienna, Austria, 2High-field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 3Division of Neuroradiology and Musculoskeletal Radiology, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 4Department of Neurology, Hietzing Hospital, Vienna, Austria, 5Center for Rare and Complex Childhood Onset Epilepsies, Member of ERN EpiCARE, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria, 6Christian Doppler Laboratory for MR Imaging Biomarkers, Vienna, Austria, 7Department of Neurology, Medical University of Vienna, Vienna, Austria, 8Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
Synopsis
Keywords: Epilepsy, High-Field MRIIn this study, structural lesions in 3T and 7T of 12 patients suffering from intractable focal epilepsy were co-registered and manually segmented using ITK-SNAP. The rendered volumes were compared with reference to 3T lesional size in FLAIR, T1 and T2-weighted sequences. Additionally, a WMS sequence was compared to 3T FLAIR as well as 7T FLAIR. Our findings illustrate that on average, 7T showed larger lesion volume in all sequences except WMS.
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