Abstract #5202

The diagnostic value of mean apparent propagator (MAP) MRI in temporal lobe epilepsy (TLE) with unilateral amygdala enlargement: A pilot study

Lu Zu^1,2, Peng Zhao², Mengxiao Liu³, Xiaoli Li⁴, Wei Zhang⁵, Yani Cheng^1,2, and Xiangtao Lin²

¹Shandong University, Jinan, China, ²Department of Radiology, Shandong Provincial Hospital, Jinan, China, ³MR scientific Marketing, Diagnostic Imaging, Siemens Healthineers Ltd, Shanghai, China, ⁴Department of Radiology, The Second People’s Hospital of Kunming, Kunming, China, ⁵The People's Hospital of Laoling, Laoling, China

Synopsis

Keywords: Epilepsy, Diffusion/other diffusion imaging techniques, mean apparent propagator (MAP)For patients with routine MRI-negative epilepsy, noninvasive imaging is important for differential diagnosis. AE might be a subtype of MRI-negative TLE. The aim of this study was to evaluate the diagnostic efficacy of MAP-MRI and traditional DTI between TLE-AE patients and healthy controls. Results showed that MSD, QIV, RTAP, RTOP from MAP-MRI and FA from DTI in amygdala can be used as an imaging indicator to identify TLE-AE(P<0.05). Furthermore, MSD, RTAP, RTOP had a significant correlation with seizure types. MAP-MRI outperformed DTI in the diagnosis of TLE-AE, and MAP-MRI is expected to contribute in probing MRI-negative epileptogenic lesions.

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