Keywords: Epilepsy, Arterial spin labelling
The early identification, evaluation and intervention are important for older people with epilepsy, which calls for techniques of high convenience, repeatability and practicality in clinical application. By applying arterial spin labeling (ASL), we detected perfusion differences between older people with epilepsy and healthy controls on whole-brain voxel-based level, and conducted linear regression between cerebral blood flow (CBF) and duration of epilepsy. Our findings revealed a mixed perfusion pattern for older people with epilepsy, and the significant correlation between CBF and duration of epilepsy. Therefore, ASL has potential value in early diagnosis and evaluation of seizure activity and severity for epilepsy.
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