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Abstract #5216

Quantitative Comparison of 1.5T and 3.0T 1H Magnetic Resonance Spectroscopy for Temporal Lobe Epilepsy

Biao Qu1, Hejuan Tan2, Min Xiao2, Dongbao Liu3, Shijin Wang4, Yiwen Zhang5, Runhan Chen6, Gaofeng Zheng1, Yonggui Yang7, Gen Yan7, and Xiaobo Qu3
1Department of Instrumental and Electrical Engineering, Xiamen University, Xiamen, China, 2Institute of Artificial Intelligence, Xiamen University, Xiamen, China, 3Biomedical Intelligent Cloud R&D Center, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Department of Electronic Science, Xiamen University, Xiamen, China, 4Department of Information & Computational Mathematics, Xiamen University, Xiamen, China, 5Department of Neurology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, China, 6National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen, China, 7Department of Radiology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, China

Synopsis

Keywords: Epilepsy, BrainThe study explored the diagnostic utility of different field strengths for the temporal lobe epilepsy (TLE) with 1H magnetic resonance spectroscopy (1H-MRS) which could be utilized to examine the concentrations of related metabolites. Four ratios of brain metabolites, including NAA/Cr, NAA/Cho, NAA/(Cho+Cr) and Cho/Cr were introduced to four control experiments with the Mann-Whitney U Test, the power analysis and the Paired T-Test adopted. Results suggested that 1.5T and 3.0T scanners might have comparable potential in distinguishing TLEs from HCs when 1H-MRS was used to identify patients with TLE.

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