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Abstract #5227

UV-Curable Hydrogels for Quantitative T1/T2 in Slice Phantoms

Szu Ting Tung1, Jolene Huey1, Michael Lustig 1, Ana Claudia Arias1, and Anita Flynn1
1Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, United States

Synopsis

Keywords: Phantoms, Multi-ContrastWe developed a high-volume, low error UV-curable hydrogel formation process that can target specific T1 and T2 parameters. Our process relies on the polymerization of water-soluble photoinitiator TPO-Lithium in acrylamide (monomer), polyethylene-glycol-diacrylate (crosslinker), de-ionized (DI) water, and paramagnetic ions. We characterize the linearizing effect of varying paramagnetic ion concentrations in determining T1 and T2 values, and present an application to construct a quantitative anatomy-mimicking brain slice phantom containing UV gels.

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