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Abstract #5242

Quantitative and qualitative analysis of left ventricular remodeling after myocardial infarction: 4D flow MRI in a swine model

Hyungkyu Huh1, Sungho Park2, Yura Ahn3, Hyun Jung Koo3, and Dong Hyun Yang3
1Department of advanced technology, K-mediHub, Daegu, Korea, Republic of, 2Kangwon National University, Chuncheon, Korea, Republic of, 3Asan Medical Center, Seoul, Korea, Republic of

Synopsis

Keywords: Flow, HeartLeft ventricular remodeling and functional changes may affect the intra-cardiac hemodynamics, however, has not yet been systematically studied. This study provides comprehensive understanding on chronic hemodynamics changes after myocardial infarction (AMI) in a swine model by using sequential cardiac magnetic resonance imaging (MRI) and 4D flow MRI. The orientations of infilling blood flow and vortex cores were shifted due to the infarcted tissue, decreasing the local rotation of the intracardiac flow as MI progresses. It’s trends also correlated well with the decreased radial strain and global function. These findings may provide new hemodynamic based diagnosis markers for MI.

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Keywords