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Abstract #5243

Indirectly Prediction of Cardiac Adverse Events Based on Hemodynamics Change Induced by Exercise Using 4D flow MRI

Jiali Li1, Qian Liu1, Min Tang1, Wanying Qi1, Qianfeng Luo1, Tao Liu1, Xiaoyong Zhang2, and Jing Chen1
1The Affiliated Hospital of Southwest Medical University, Luzhou, China, 2Clinical Science, Philips Healthcare, Chengdu, China

Synopsis

Keywords: Heart, CardiovascularIn this study, we aimed to implement and evaluate methods for indirectly prediction of cardiac adverse events inside athletes based on hemodynamic changes in heart and aorta of four-dimensional (4D) flow MRI. The results showed that advanced parameters such as wall shear stress, energy loss and relative differential pressure were increased in athletes' hearts with late gadolinium enhancement and/or cardiac remodeling compared to controls, and the probability of remodeling in the exercising heart could be predicted by predictive models. This suggests that exercise-induced hemodynamic changes could be detected by 4D flow, which could predict the occurrence of adverse cardiovascular events.

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