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Abstract #5244

High-resolution and highly accelerated T2 mapping in kidney cancer treatment-response and subtype differentiation

Ines Horvat-Menih1, Hao Li1, Andrew N Priest1, Iosif Mendichovszky1, Susan Francis2, Anne Y Warren3, Sarah J Welsh4, Grant Stewart5, and Ferdia Gallagher1
1Department of Radiology, University of Cambridge, Cambridge, United Kingdom, 2University of Nottingham, Nottingham, United Kingdom, 3Department of Histopathology, CUH NHS Foundation Trust, Cambridge, United Kingdom, 4Department of Oncology, University of Cambridge, Cambridge, United Kingdom, 5Department of Surgery, University of Cambridge, Cambridge, United Kingdom

Synopsis

Keywords: Kidney, Cancer, T2-mapping

Here we have applied newly developed T2 mapping methods based on Echo Merging and k-t Undersampling with Reduced flip Angles (TEMPURA) in the clinical setting of kidney cancer for the first time. The accelerated and high-resolution TEMPURA approach showed high promise in quantitatively and qualitatively evaluating the treatment response and differentiating between high vs. low grade clear-cell renal cell carcinoma, as well as different kidney tumor subtypes.

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