Abstract #5255

Framewise distortion correction in Multi-echo Echo Planar Imaging

Andrew N. Van^1,2, M. Dylan Tisdall³, Timothy O. Laumann⁴, David F. Montez^2,4, Damien A. Fair^5,6,7, and Nico U.F. Dosenbach^1,2,8,9

¹Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, United States, ²Department of Neurology, Washington University School of Medicine, St. Louis, MO, United States, ³Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, ⁴Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States, ⁵Institute of Child Development, University of Minnesota Medical School, Minneapolis, MN, United States, ⁶Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, United States, ⁷Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, United States, ⁸Department of Radiology, Washington University School of Medicine, St. Louis, MO, United States, ⁹Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States

Synopsis

Keywords: Data Processing, fMRIEcho Planar Imaging (EPI) suffers from off-resonance image distortion due to B0 inhomogeneities. These distortions are typically corrected by separate field map acquisitions, but only allow for sparse temporal sampling of B0 inhomogeneity. This approach prevents distortion correction if changes in the B0 field occur over time due to motion. Here, we present a method of correcting off-resonance distortion by computing a time series of field maps using phase information from multi-echo (ME) EPI data. We show that our method produces corrections comparable to the current standard of distortion correction, in addition to enabling frame-by-frame correction in functional MRI data.

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