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Abstract #5262

The impact of data normalization and plane view in deep learning for classifying multiple sclerosis subtypes using MRI scans.

Mahshid Soleymani1, Yunyan Zhang2, and Mariana Bento2
1Biomedical Engineering, University of Calgary, Calgary, AB, Canada, 2University of Calgary, Calgary, AB, Canada

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Data ProcessingDisease activity varies between patients with multiple sclerosis (MS), and patients who have a greater risk of developing a progressive course require more aggressive therapies earlier. However, differentiating disease severity is challenging using conventional methods as the disease often progresses silently. By taking advantage of one of the most advanced quantitative methods, convolutional neural networks, we aim to develop a new deep learning model to differentiate two common MS subtypes: relapsing-remitting course from secondary progressive phenotype. This study focuses on varying image pre-processing techniques and using different data views using conventional brain MRI.

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Keywords