Abstract #5267

Optimized B₀ and B₁⁺insensitive RF pulses for non-selective T2 and diffusion preparation

Xuetong Zhou^1,2, Brian A. Hargreaves^1,2,3, and Philip K. Lee²

¹Department of Bioengineering, Stanford University, Stanford, CA, United States, ²Department of Radiology, Stanford University, Stanford, CA, United States, ³Department of Electrical Engineering, Stanford University, Stanford, CA, United States

Synopsis

Keywords: New Signal Preparation Schemes, Data AcquisitionThe performance of conventional T2 or diffusion preparation using linear phase pulses or adiabatic pulses is limited by the B₁⁺ and B₀ field inhomogeneities, particularly relevant in body imaging. In this work, we proposed a numerical optimization strategy to design RF pulse pairs for non-selective T2 or diffusion preparation that perform robustly over a wide range of B₁⁺ and B₀ variations. Phantom and in vivo experiments compared the performance of preparation using the optimized pulses to that of linear-phase and adiabatic pulses.

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Optimized B0 and B1+ insensitive RF pulses for non-selective T2 and diffusion preparation

Synopsis

Optimized B₀ and B₁⁺insensitive RF pulses for non-selective T2 and diffusion preparation