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Abstract #5275

Using Convolutional Neural Networks to detect and remove out-of-voxel MRS artefacts

Aaron T Gudmundson1,2, Kathleen E Hupfeld2,3, Yulu Song2,4, Helge J Zöllner1,2, Christopher W. Davies- Jenkins1,2, İpek Özdemir1,2, Georg Oeltzschner2,3, and Richard A E Edden1,2
1The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, 3The Russell H. Morgan Department of Radiology and Radiological SciencesRadiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 4The Russell H. Morgan Department of Radiology and Radiological Sciences Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Spectroscopy, Out-of-voxel (OOV), MRS, Artefacts, Deep Learning, Convolutional Neural NetworkOut-of-voxel (OOV) artefacts, or echoes, are common in-vivo artefacts seen in MRS data. These artefacts are typically not identified until post-processing and are challenging to remove without modifying the underlying data. Here, we developed 2 Convolutional Neural Networks (CNNs) to overcome OOV artefacts at different stages. The first network (CNN1) was designed to identify OOV artefacts in single average data and offer a real-time assessment during data acquisition. The second (CNN2) predicts the OOV artefact to subtract during post-processing without impacting the metabolite data.

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