Abstract #5282

Demonstration of Distinct Iron Deposition Patterns in Gliomas using 7T Quantitative Susceptibility Mapping

Demetrius Eugene Lee, B.S.^1,2, Kristina Vineis, B.S.^1,2, Laiz Godoy, M.D.^1,2, Lisa Desiderio, RT (R)(MR)^1,2, Suyash Mohan, M.D.^1,2, and Sanjeev Chawla, Ph.D^1,2

¹Radiology, Perelman School of Medicine, Philadelphia, PA, United States, ²University of Pennsylvania, Philadelphia, PA, United States

Synopsis

Keywords: Tumors, Blood vessels, Glioma

Evidence has shown that abnormal iron levels and gliomas are heavily correlated. Due to this, iron presents a possibility to serve as a glioma biomarker. This study will utilize susceptibility-weighted imaging (SWI) to identify the glioma, and quantitative susceptibility mapping (QSM) to explicitly classify iron deposits in the glioma on an ultra-high field (7T) scanner.

A total of 6 untreated glioma patients with high- and low-grade gliomas underwent 7T QSM. Patients with high-grade gliomas showed distinct, geometric iron deposits that low-grade gliomas did not. These results illustrate that 7T QSM may be helpful in classifying low- and high-grade gliomas.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.