Abstract #5292

Adapting the NODDI-GBSS Framework for the 1-Month Infant Brain

Marissa DiPiero^1,2, Patrik Goncalves Rodrigues², Hassan Cordash², Jose Guerrero Gonzalez², Richard J. Davidson^3,4,5, Andrew Alexander^2,3,6, and Douglas C. Dean III^2,6,7

¹Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI, United States, ²Waisman Center, University of Wisconsin-Madison, Madison, WI, United States, ³Department of Psychiatry, University of Wisconsin-Madison, Madison, WI, United States, ⁴Department of Psychology, University of Wisconsin-Madison, Madison, WI, United States, ⁵Center for Healthy Minds, University of Wisconsin-Madison, Madison, WI, United States, ⁶Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁷Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Neuro, Gray MatterThe brain’s cytoarchitecture undergoes highly dynamic morphological changes during early life that establish the brain’s structural and functional framework and lays the foundation for future cognitive and behavioral skills. While differences in early cortical organization are thought to subserve future behavioral and psychiatric challenges, little is known regarding cortical organization in early life. For the first time, we adapt the NODDI-GBSS framework for the infant brain while keeping the data in its native diffusion space. We show feasibility for cortical skeletonization and show relationships with age across the GM microstructure within the first month of life.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.