Abstract #5294

Memory and learning relationships with hippocampal morphometry and multi-modal connectivity after pediatric severe TBI

Jose Guerrero-Gonzalez¹, Gregory Kirk², Rasmus Birn¹, Erin Bigler³, Katherine Bowen⁴, Aimee Broman⁵, Bedda Rosario⁶, Warwick Butt⁷, Sue Beers⁸, Michael Bell⁹, Peter Ferrazzano¹⁰, and Andrew Alexander¹

¹Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, ²Waisman Center, University of Wisconsin - Madison, Madison, WI, United States, ³Department of Psychology and Neuroscience Center, Brigham Young University, Provo, UT, United States, ⁴Seattle Children’s Hospital, Seattle, WA, United States, ⁵Biostatistics, University of Wisconsin - Madison, Madison, WI, United States, ⁶Epidemiology, University of Pittsburgh, Pittsburgh, PA, United States, ⁷Critical Care, Faculty of Medicine, Melbourne University, Melbourne, Australia, ⁸Psychiatry, University of Pittsburgh, Pittsburgh, PA, United States, ⁹Pediatrics, Children’s National Medical Center, Washington, DC, United States, ¹⁰Pediatrics, University of Wisconsin - Madison, Madison, WI, United States

Synopsis

Keywords: Neuro, Traumatic brain injury

Traumatic brain injury in adolescents is a major public health concern, leading to tens of thousands of hospitalizations in the U.S. each year. Our study aims to identify multimodality imaging biomarkers of long-term neurocognitive outcome after severe adolescent TBI. For this investigation we explored memory performance using the California Verbal Learning Test (CVLT) in relation to structural and functional connectivity of the memory network, as well as hippocampal volume and fornix microstructure.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.