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Abstract #5296

Structural and Functional Brain Alterations in Children with Autism Spectrum Disorder

Di Zhou1, Ting Hua1, Xiance Zhao2, and Guangyu Tang1
1Department of Radiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China, 2Philips Healthcare, Shanghai, China

Synopsis

Keywords: Neuro, fMRI (resting state)MRI is an important tool available to detect brain functional and structural abnormalities of autism spectrum disorder (ASD) patients. In this study, we found that children with ASD have increased changes in structure and both increased and decreased changes in function in the brain, which suggests that there may be some underlying pathogenic mechanism in the brain of ASD. With the combination of brain structural and functional analysis can provide a new imaging perspective for understanding the neural mechanism of ASD.

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