Abstract #5303

Functional Brain Alterations in Children with Autism Spectrum Disorder after Fecal Microbiota Transplantation

Di Zhou¹, Ting Hua¹, Xiance Zhao², and Guangyu Tang¹

¹Department of Radiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China, ²Philips Healthcare, Shanghai, China

Synopsis

Keywords: Neuro, fMRI (resting state)

MRI is an important tool available to detect brain functional and structural abnormalities of autism spectrum disorder (ASD) patients. In this study, we combined fecal microbiota transplantation (FMT) and neuroimages to follow-up and explore the change in functional activity in children with ASD. The combination of FMT and MRI can provide a new imaging perspective for understanding the neural mechanism of gut microbiota in ASD.

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