Keywords: Head & Neck/ENT, MR Fingerprinting, Nasopharyngeal carcinoma; treatment response; Synthetic MRIAlmost 80% nasopharyngeal carcinoma patients are diagnosed with locoregionally-advanced stage at the time of initial diagnosis. Early detection of treatment response is important for adjusting therapy regimens. SyMRI could not only generate multi-contrast images (including T1WI, T2WI and PDWI) in a single scan, but also generate quantitative T1, T2 and PD maps. Our study demonstrated that SyMRI combined with histogram analysis could non-invasive predict early treatment response. The predict performance of combined SyMRI and clinical factors was significantly higher than clinical only or TNM stage only.
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