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Abstract #5359

Observation of the Cerebral Perforating Arteries around Circle of Willis Using Compressed Sensing Time-of-Flight at 7T

Qingle Kong1, Zhe Zhang2,3, and Jing Jing2,3,4
1MR Collaboration, Siemens Healthineers Ltd., Beijing, China, 2Tiantan Neuroimaging Center of Excellence, Beijing, China, 3Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Centre for Neurological Diseases, Beijing, China, 4Beijing Tiantan Hospital, Capital Medical University, Neurology Department, Beijing, China

Synopsis

Keywords: Atherosclerosis, Vessels, perforating arteries, ultra high resolutionThe impairment of microvessels can lead to neurologic diseases such as stroke and vascular dementia. Perforating arteries imaging requires an extremely high resolution due to their small caliber size. In this study, for the first time, the feasibility of noninvasive visualization of perforators around Circle of Willis in vivo was demonstrated by using 7T compressed sensing TOF. The number of stems and branches of the perforators was then calculated. The origin and anatomical distribution of the perforating arteries are described. This work revealed that ultra-high-resolution CS TOF might be a promising method for detecting microvasculopathies of cerebral vascular diseases.

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