Abstract #5372

Diffusion Tensor MRI in a Rat C6 Glioma Model at 9.4T

Maryam Mozaffari^1,2, Naila Rahman^1,2, Patrick McCunn^1,2, Nivin Nystrom^1,2, Alex Li², Miranda Bellyou², Corey Baron^1,2, Timothy Scholl^1,2, and Robert Bartha^1,2

¹Medical Biophysics, Western University, London, ON, Canada, ²Centre for Functional and Metabolic Mapping, Robarts Research Institute, London, ON, Canada

Synopsis

Keywords: Diffusion/other diffusion imaging techniques, Brain, Animal modelThe objective of this study was to characterize the diffusion properties of water in and around C6 glioma tumors in rats at 9.4T. DTI showed differences in some diffusion metrics between tumor tissue and surrounding tissues. Significantly higher FA, MD, and AD values were found in the tumor region compared to the contralateral side. DTI measurement of tumor microstructure and its surroundings could help to enhance the efficacy of diagnosis in different human malignancies.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.