Abstract #5425

Metabolic Tumor Volume prediction by using Hand Craft Fuzzy Rule Base System (FRBS) on Simultaneous PET/MRI

Pradeep Singh Negi^1,2, Shashi Bhushan Mehta^1,2, and Amarnath Jena^1,2

¹Department of Molecular Imaging and Nuclear Medicine, PET SUITE: Indraprastha Apollo Hospitals and House of Diagnostics, Delhi, India, ²Department of Physics, Vivekananda Global University, Jaipur, India

Synopsis

¹⁸F-FDG PET/MRI can be helpful for diagnosing, staging, restaging, and assessing the post therapeutic response in breast cancer patients. Metabolic tumor volume (MTV) may be more reliable but volumetric assessments of FDG PET needs correct tumor segmentation. We have proposed hand craft fuzzy rule base system to improve tumor volume by using simultaneous PET/MRI for accurate MTV estimation. Four breast cancer patients underwent FDG PET/MRI for staging purpose. Pathological tumor volume was compared with MRI volume, K^trans volume and MTV computed by hand craft fuzzy rule and the results showed fuzzified tumor volume were more accurate compared with other volumes.

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