Abstract #0023

Is edema of malignant glioma different from edema of other tumors? Analysis of time dependent diffusion image using ternary plot method

Toshiaki Taoka¹, Rintaro Ito¹, Rei Nakamichi², Toshiki Nakane², Kazushige Ichikawa³, Takaya Mori⁴, Ozaki Masanori⁴, Nobuyasu Ichinose⁴, Yoshiki Tanaka⁵, and Shinji Naganawa²

¹Department of Innovative Biomedical Visualization (iBMV), Nagoya University, Nagoya, Japan, ²Department of Radiology, Nagoya University, Nagoya, Japan, ³Department of Radiological Technology, Nagoya University, Nagoya, Japan, ⁴Canon Medical Systems Corporation, Otawara, Japan, ⁵SORD Corporation, Tokyo, Japan

Synopsis

Keywords: Tumors (Pre-Treatment), Diffusion/other diffusion imaging techniques

Motivation: The edema around a malignant glioma contains infiltrating tumor cells. The motivation for this study was to determine the characteristics of the edema of malignant glioma.

Goal(s): The goal is to evaluate the characteristics of edema around malignant gliomas using a combination of the oscillating gradient spin echo and pulsed gradient spin echo.

Approach: The ternary plot method is used to evaluate the characteristics of edema by using a plot of existing tissue as an internal reference.

Results: Edema of malignant gliomas showed a different distribution in relation to the internal reference in the ternary plot method compared to edema of other tumors.

Impact: Ternary plot method was used to present pixel values obtained from oscillating gradient spin echo and pulsed gradient spin echo, and existing tissues were evaluated as internal references, which was thought to enable evaluation of the histological properties of edema.

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