Abstract #0094

Free-running fat-suppressed radial whole-heart 4D flow using OptiPulse

Robin Ferincz¹, Xavier Sieber¹, Efena Akporeha¹, Mariana B. L. Falcao¹, Jérôme Yerly², Michael Markl³, Jonas Richiardi¹, Ruud B. van Heeswijk¹, Matthias Stuber¹, and Christopher William Roy¹

¹Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Switzerland, Lausanne, Switzerland, ²Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, Lausanne, Switzerland, ³Department of Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA, Chicago, IL, United States

Synopsis

Keywords: Flow, Heart, Flow, Fat, Whole-heart, Congenital Heart Disease

Motivation: Free-running radial 4D flow has been shown to enable accurate whole-heart quantification and visualization of hemodynamics. However, unsuppressed fat signal can lead to artifacts, which may compromise image quality and cause errors in flow quantification.

Goal(s): Our study therefore aims to reduce fat signal in radial 4D flow MRI.

Approach: We integrated a novel b-splines iteratively optimized water-excitation RF pulse generated with a previously described framework (OptiPulse) into a radial 4D flow sequence to suppress the signal from fat.

Results: We successfully integrated OptiPulse in radial 4D flow to suppress fat signal and demonstrated comparable quantitative flow assessment to non-fat-suppressed 4D flow.

Impact: The integration of b-splines iteratively optimized water-excitation RF pulses (OptiPulse) into a free-running radial whole-heart 4D flow sequence leads to significantly reduced fat-signal in a promising step towards more robust hemodynamic assessment in patients with large amounts of adipose tissue.

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