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Abstract #0152

A MR Fingerprinting Development Kit (MRFDK) for Quantitative 3D Brain Imaging

Rasim Boyacioglu1, Thomas Kluge2, Guido Buonincontri2, Wei-Ching Lo3, Stephan Kannengiesser2, Mathias Nittka2, Dan Ma4, Mark A Griswold1, and Yong Chen1
1Radiology, Case Western Reserve University, Cleveland, OH, United States, 2Siemens Healthineers AG, Erlangen, Germany, 3Siemens Medical Solutions USA, Boston, MA, United States, 4Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: MR Fingerprinting, MR Fingerprinting

Motivation: MRF acquisitions rely on offline reconstructions due to their computationally intensive processing pipelines which hinders integration into clinical workflows.

Goal(s): To introduce and test a development kit for MRF, enabling 1) efficient whole brain 3D MRF acquisitions, 2) embedded dictionary calculation, and 3) rapid online post-processing.

Approach: The method was evaluated with phantom and in vivo brain imaging for multiple MRF variants and receive coils.

Results: Due to full scanner integration, high-quality T1 and T2 maps were presented on the host computer within 1 min after the MRF scan was completed, enabling timely visualization of the outcome.

Impact: The MRF development kit has high potential to promote reproducibility, large-scale clinical evaluation and translation of the novel MRF technique.

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Keywords