Keywords: Liver, Liver, DWI, MRE, Liver fibrosis, RegGAN, CBAM
Motivation: Liver biopsy is the standard clinical approach for diagnosing liver fibrosis. However, its invasiveness and possibility of sampling errors impose inherent limitations.
Goal(s): To evaluate the reproducibility and reliability of the virtual MRE based on DWI and compare it with MRE to assess its efficiency in diagnosing liver fibrosis.
Approach: RegGAN was employed to forecast MRE and rectify the outcomes. And CBAM was utilized to quantify the influence of diverse b-values in DWI.
Results: RegGAN-CBAM demonstrates favorable performance in both image and stiffness prediction of MRE. The liver fibrosis grading based on stiffness predictions demonstrates a high level of accuracy and sensitivity.
Impact: The prediction methodology of 3D MRE based on DWI exhibits a notable level of diagnostic efficiency and reliability. This approach serves as a non-invasive method with practical applicability in the clinical assessment of liver fibrosis.
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