Keywords: Hyperpolarized MR (Gas), Contrast Agent, Dynamic Imaging of Respiratory Function
Motivation: The study aims to refine lung disease diagnosis through dynamic imaging, surpassing conventional breath-hold MRI limitations.
Goal(s): This research aims to confirm the efficacy of a new 4D dynamic HXe MRI method for real-time lung function imaging, enhancing our grasp of diseases like COPD.
Approach: Our method employs synchronized 4D dynamic MRI to differentiate lung function in healthy individuals, COPD sufferers, and a smoker, revealing subtle health variations.
Results: Dynamic imaging revealed consistent ventilation in healthy lungs but identified irregularities and a novel reversed RBC:Gas ratio pattern in COPD, indicating significant alterations in gas exchange dynamics.
Impact: This study enhances understanding of COPD and could shift diagnostic and treatment practices, paving the way for targeted therapies and improved patient outcomes.
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