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Abstract #0280

Accuracy of Measuring Opening and Closing Characteristics of the Aortic Valve with SPEEDI MRI

Qingfei Luo1, Yosman Dhar1,2, Alessandro Scotti1, and Xiaohong Joe Zhou1,3
1Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL, United States, 2College of Medicine, University of Illinois at Chicago, Chicago, IL, United States, 3Departments of Radiology, Neurosurgery, and Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States

Synopsis

Keywords: Valves, Valves, SPEEDI, sub-millisecond, high temporal resolution

Motivation: get-SPEEDI, a recently published pulse sequence, offers a promising MRI technique for imaging the rapid dynamics of the aortic valve (AV) opening and closing with sub-millisecond temporal resolution.

Goal(s): This study aims to assess the accuracy of measuring the AV dynamics with get-SPEEDI by comparing its performance with transthoracic ultrasound, which is the gold standard clinically.

Approach: Ultrasound echocardiograms and get-SPEEDI MR images of AV were acquired in healthy human subjects with 0.6- and 0.8-ms temporal resolution, respectively.

Results: There were no statistically significant differences between get-SPEEDI and ultrasound in the measurements of AV opening and closing dynamics and the maximum AV area.

Impact: The dynamic characteristics of the aortic valve measured with get-SPEEDI MRI agree well with the ultrasound measurements. get-SPEEDI MRI provides a new imaging tool for diagnosis of aortic valve diseases.

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Keywords