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Abstract #0294

Investigating Phase-Cycled bSSFP Imaging for Functional Lung Imaging in 2-Year-Olds After Congenital Diaphragmatic Hernia Repair

Efe Ilıcak1,2, Safa Özdemir1,2, and Frank Gerrit Zöllner1,2
1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 2Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

Synopsis

Keywords: Lung, Lung, Functional, Pulmonary, non-contrast-enhanced

Motivation: bSSFP-based non-contrast-enhanced imaging is a promising alternative for functional lung imaging in pediatric patients. However, bSSFP acquisitions suffer from magnetic field inhomogeneities.

Goal(s): Our goal is to investigate phase-cycled bSSFP acquisitions as a robust alternative in pediatric functional lung imaging.

Approach: We acquired dynamic images using conventional and phase-cycled bSSFP acquisitions at 1.5T, from five 2-year-old patients after congenital diaphragmatic hernia repair. The images were non-rigid registered to a reference frame and functional maps were obtained using dynamic mode decomposition technique.

Results: We have successfully obtained functional maps in all patients and observed a trend toward improved ventilation map homogeneity using phase-cycled acquisitions.

Impact: Pulmonary functional maps obtained via non-contrast-enhanced bSSFP acquisitions may suffer from field inhomogeneity artifacts. Here, we investigate phase-cycled bSSFP imaging in 2-year-old congenital diaphragmatic hernia patients, and show improved robustness, which may be beneficial for lung function assessments.

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