Abstract #0299

Brain temperature and its relation to cognitive status in traumatic brain injury: a whole-brain magnetic resonance spectroscopic imaging study

Maho Kitagawa¹, Kagari Abiko^2,3, Sulaiman Sheriff⁴, Andrew A Maudsley⁴, Daisuke Sawamura⁵, and Khin Khin Tha^1,6

¹Department of Biomarker imaging Science, Graduate School of Biomedical Science and Engineering, Hokkaido University, Sapporo, Japan, ²Department of Rehabilitation, Hokkaido University Hospital, Sapporo, Japan, ³Department of Rehabilitation, Sapporo Azabu Neurosurgical Hospital, Sapporo, Japan, ⁴Department of Radiology, University of Miami School of Medicine, Miami, FL, United States, ⁵Department of Rehabilitation Science, Hokkaido University Faculty of Health Sciences, Sapporo, Japan, ⁶Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, Sapporo, Japan

Synopsis

Keywords: Traumatic Brain Injury, Thermometry, Brain temperature

Motivation: The long-term outcome, i.e., the impact of injury on life, may be underestimated in patients with mild-to-moderate TBI. Cognitive deficit, a sequela of TBI and a significant social burden, is difficult to assess in uncooperative patients.

Goal(s): To compare brain temperature between control and TBI groups, and to assess the relationship between brain temperature and cognitive status in TBI group.

Approach: Brain temperature of patients was estimated noninvasively by WB-MRSI and compared to controls; the association between brain temperature and cognitive status was also assessed in the TBI group.

Results: Significant brain temperature reductions in the TBI group were associated with cognitive decline.

Impact: The strong correlation between brain temperature and cognitive performance in the TBI group indicates that attention decreases as brain temperature decreases. Brain temperature may become as a quantitative indicator of cognitive status in patients with subacute to chronic TBI.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.