Keywords: Traumatic Brain Injury, Traumatic brain injury, Repetitive head impacts, Magnetic resonance elastography
Motivation: The growing concern about subconcussive, repetitive head impacts (RHI) has prompted the need for non-invasive RHI detection methods.
Goal(s): To understand if there are alterations of the skull-brain interface due to RHI exposure and explore potential imaging biomarkers for characterizing RHI.
Approach: Four MR Elastography (MRE)-based parameters were compared between RHI(-) and RHI(+) groups, encompassing assessment of cortical stiffness, capabilities of motion dampening, and strain mediation at the skull-brain interface.
Results: Our findings revealed increased cortical stiffness, rotational transmission ratio, and adjusted NOSS in individuals with high RHI exposure, suggesting a degeneration of the skull-brain interface decoupling performance.
Impact: This study sheds light on RHI-induced changes at the skull-brain interface, proposing three potential non-invasive biomarkers for monitoring such alterations. These findings hold promise for aiding medical professionals in identifying individuals at high RHI exposure risk.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords