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Abstract #0385

Unified Diffusion model for Multi-contrast Ensembling Synthesis

Yeeun Lee1, Yejee Shin2, Doohyun Park2, Geonhui Son2, Taejoon Eo2,3, and Dosik Hwang2,4,5,6
1School of Artificial Intelligence, Yonsei University, Seoul, Korea, Republic of, 2School of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of, 3PROBE Medical Inc., Seoul, Korea, Republic of, 4Center for Healthcare Robotics, Korea Institute of Science and Technology, Seoul, Korea, Republic of, 5Department of Oral and Maxillofacial Radiology, Yonsei University College of Dentistry, Seoul, Korea, Republic of, 6Department of Radiology and Center for Clinical Imaging Data Science (CCIDS), Yonsei University College of Medicine, Seoul, Korea, Republic of

Synopsis

Keywords: Acquisition Methods, Brain

Motivation: Scanning for multi-contrast MR images is time-consuming. To reduce scan time, it is beneficial to explore methods for efficiently synthesizing target contrast images from existing contrast scans.

Goal(s): To address the stability issues encountered when dealing with multi-contrast MR image domains individually, we propose a methodology for effectively synthesizing images while incorporating multi-contrast domains.

Approach: Our model is a novel unified diffusion model (UDM) that improves the synthesis of detailed anatomical structures in target contrast images through an ensemble method.

Results: UDM demonstrates effectiveness across multiple domains, outperforming existing methodologies in synthesizing images for each contrast domain.

Impact: By reducing scan times and costs for multi-contrast imaging, UDM facilitates prognosis prediction and treatment planning. This method is not only usable for image synthesis but also extendable to various applications such as reconstruction.

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