Abstract #0393

Real-time motion correction and multicoil shim array B0 update for whole-brain MR spectroscopic imaging

Ovidiu Cristian Andronesi¹, Robert Frost¹, Nicolas Sebastian Arango², Nutandev Bikkamane Jayadev³, Yulin Chang³, Paul Wighton¹, Malte Hoffmann¹, Jason Stockmann¹, and Andre van der Kouwe¹

¹Radiology, Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts General Hospital, Boston, MA, United States, ²Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ³Siemens Medical Solutions, Boston, MA, United States

Synopsis

Keywords: Motion Correction, Motion Correction, Real-time shimming, Multicoil shim array, Metabolic Imaging

Motivation: Very high quality of MR spectroscopic imaging (MRSI) data is needed for robust and reproducible metabolite quantification. This critically depends on the B₀ shimming and scan stability. Integrated RF-receive/B₀-shim arrays significantly improve spectral quality.

Goal(s): Real-time motion correction and multicoil shimming update with an integrated RF-receive/B₀-shim array for robust whole-brain MRSI.

Approach: We developed a rapid navigator for head tracking and B0 fieldmapping in combination with rapid processing for real-time update of multicoil shim currents and MRSI localization.

Results: Real-time motion correction and multicoil shimming provides significantly narrower linewidth, higher signal-to-noise, reduced quantification errors and reproducible metabolic imaging.

Impact: Whole-brain MRSI is a unique method for non-invasive mapping of brain neurochemistry, and in combination with real-time motion correction and multicoil shim array update provides robust and reproducible quantitative metabolic imaging for clinical use.

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