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Abstract #0466

Local SAR and Uncertainty Estimation for Brain Imaging by Bayesian Deep Learning

E.F. Meliado1,2,3, S. Mandija2,4, C.A.T. van den Berg2,4, and A.J.E. Raaijmakers1,2,5
1Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 2Computational Imaging Group for MR diagnostics & therapy, Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands, 3Tesla Dynamic Coils BV, Zaltbommel, Netherlands, 4Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, 5Biomedical Image Analysis, Dept. Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands

Synopsis

Keywords: Safety, Safety, specific absorption rate; local SAR; deep learning; Bayesian deep learning; uncertainty estimation

Motivation: Local SAR cannot be measured during an MRI examination. Deep learning approaches are proving to be a solution for on-line subject-specific SAR assessment.

Goal(s): The brain is the region of greatest clinical interest for ultra-high field MRI. Therefore, we apply for brain imaging a deep learning approach presented for local SAR assessment for body imaging.

Approach: The Bayesian deep-learning approach maps the relation between subject-specific complex B1+-maps and the corresponding local SAR distribution, and predicts the spatial distribution of uncertainty at the same time

Results: The Bayesian deep-learning approach for local SAR assessment in brain outperforms the previous application for prostate imaging.

Impact: The application of Bayesian deep-learning can allow the reduction of overly conservative RF safety constraints that limit the performance of UHF-MRI. Furthermore, the joint estimation of uncertainty can help the acceptance of such methods in clinical contexts.

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Keywords