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Abstract #0475

A 48-channel multi-coil shim array for B0 inhomogeneities correction in the NHP brain at 7T.

Elias Djaballah1, Anojan Uthayakumar2, Martin Bouchet 1, André Kalouguine1, Alexis Amadon2, and Qi ZHU1
1Cognitive Neuroimaging Unit, INSERM, CEA, Université Paris-Saclay, NeuroSpin Center, GIF-SUR-YVETTE, France, 2BAOBAB, Université Paris-Saclay, CEA/Joliot/NeuroSpin, GIF-SUR-YVETTE, France

Synopsis

Keywords: Shims, High-Field MRI, non-human primate, B0 shimming, fMRI

Motivation: Functional MRI faces challenges due to B0 field inhomogeneities, which are amplified in non-human primate studies, especially at ultra-high fields.

Goal(s): Our aim was to develop a Multi-Coil Array (MCA) specifically designed for whole brain shimming of non-human primates.

Approach: A semi-heuristic approach was used to design an MCA, based on the Principal Components Analysis of subject-optimal stream functions. The MCA was then constructed and used to image an in-vivo NHP brain.

Results: The designed MCA effectively reduced B0 inhomogeneities in the primate brain, resulting in significant improvements in B0 homogenization and enhanced image quality in functional MRI images at 7T.

Impact: The development of a Multi-Coil Shim Array designed specifically for non-human primates significantly improves functional MRI image quality by effectively reducing B0 inhomogeneities. This advancement could pave the way for more accurate and detailed primate brain studies at ultra-high fields.

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