Abstract #0522

Quantitative Abdominal Sodium MRI Combined with 32-Channel Proton pTx MRI at 7T in a Large Field-of-View

Anna K. Scheipers^1,2, Stephan Orzada¹, Johannes Grimm^1,2, Jana Losch^1,2, Thomas M. Fiedler¹, Armin M. Nagel^1,3, Sebastian Schmitter¹, Mark E. Ladd^1,2,4, and Tanja Platt¹

¹Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Faculty of Physics and Astronomy, Heidelberg University, Heidelberg, Germany, ³University Hospital Erlangen, Institute of Radiology, Friedrich‐Alexander‐Universität Erlangen‐Nürnberg (FAU), Erlangen, Germany, ⁴Faculty of Medicine, Heidelberg University, Heidelberg, Germany

Synopsis

Keywords: High-Field MRI, Quantitative Imaging, 23Na, Sodium, parallel transmit (pTx), TIAMO, tissue sodium concentration (TSC), 7T whole-body coils, Body, Data Acquisition, High-Field MRI, Hybrid & Novel Systems Technology, Kidney, Liver, Multi-Contrast, Non-Proton, Whole Body

Motivation: ²³Na MRI enables the quantification of the tissue sodium concentration. A large field-of-view is beneficial for abdominal MRI, especially if several organs are of interest. Due to lower resolution compared to ¹H MRI, ²³Na MRI is less suited for segmentation.

Goal(s): To combine large field-of-view ¹H and quantitative abdominal ²³Na MRI in the same position at 7T.

Approach: Employing a custom-built ²³Na radiofrequency coil and reference vial setup together with a 32-channel proton pTx array to allow dual-nuclei MRI in the same position.

Results: Combination of large field-of-view ¹H and quantitative ²³Na MRI of the human torso is feasible at 7T in ≤42min.

Impact: This work shows the feasibility of combined ¹H and ²³Na imaging at 7T in a large field-of-view both under free breathing, laying the ground work for an accurate evaluation of the tissue sodium concentration in several organs at once.

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