Meeting Banner
Abstract #0525

T2 Mapping of the Prostate at 7 Tesla: A Feasibility Study

Gabriele Bonanno1,2,3, Bernd Jung3,4, Roland Kreis2,3, Sebastian Schmitter5,6,7, Verena C Obmann3,4, Tobias Kober8,9,10, and Tom Hilbert8,9,10
1Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Bern, Switzerland, Bern, Switzerland, 2Magnetic Resonance Methodology, Institute of Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Switzerland, Bern, Switzerland, 3Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland, Bern, Switzerland, 4Dept. of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, Switzerland, Bern, Switzerland, 5Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, Berlin, Germany, 6Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, Heidelberg, Germany, 7Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, Minneapolis, MN, United States, 8Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, Lausanne, Switzerland, 9Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, Lausanne, Switzerland, 10LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, Lausanne, Switzerland

Synopsis

Keywords: High-Field MRI, Prostate

Motivation: T2 relaxometry has shown potential to distinguish cancer from prostate tissue at 3T. Despite potential gains in resolution, it has been little explored at ultra-high field due to challenging B1+ homogeneity and efficiency.

Goal(s): To investigate feasibility of prostate T2 mapping at 7T using a robust RF shimming procedure.

Approach: We evaluated conventional 2D multi-echo spin echo and an optimized 3D T2-prepared segmented-FLASH sequence.

Results: Spin-echo T2 maps showed good quality but required long acquisition times for limited coverage. The T2-prepared FLASH sequence showed similar values while providing higher scan efficiency, lower SAR, and whole-organ coverage at the cost of higher motion sensitivity.

Impact: Quantitative T2 mapping at ultra-high field is challenging due to acquisition time and SAR restrictions, especially in the pelvic area. The methods investigated here may be used in future routine to detect and grade prostate cancer.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract Presentation Video

Keywords