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Abstract #0577

Cardiac Magnetic Resonance Fingerprinting for Simultaneous T1 and T2 Mapping at 0.55T

Carlos Castillo-Passi1,2,3, Carlos Velasco1, Donovan Tripp1, Karl P. Kunze1,4, Radhouene Neji1, Pablo Irarrazaval3,5,6, René M. Botnar1,2,3,7,8, and Claudia Prieto1,3,7
1King's College London, London, United Kingdom, 2Intitute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 3Millennium Institute for Intelligent Healthcare Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 4MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, 5Insititute for Biological and Medical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, 6Electrical Engineering Department, Pontificia Universidad Católica de Chile, Santiago, Chile, 7School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 8Hans Fischer Senior Fellow Award, Institute for Advanced Study at Technical University of Munich, Munich, Germany

Synopsis

Keywords: MR Fingerprinting, Cancer

Motivation: Cardiac MRF (cMRF) allows for comprehensive myocardial tissue characterization in a single scan and has been investigated at 1.5T/3T. However, cMRF has not been demonstrated at low-field.

Goal(s): Investigate the feasibility of a bSSFP-cMRF sequence for simultaneous T1 and T2 mapping at 0.55T.

Approach: The proposed approach considers bSSFP radial readouts with varying IR and T2-preparation pulses over 16 heartbeats. bSSFP-cMRF was evaluated in phantoms and healthy subjects in comparison to reference maps.

Results: bSSFP-cMRF at 0.55T shows excellent agreement with reference values in phantom and good image quality in healthy subjects with T1 and T2 values agreeing with the literature.

Impact: The simultaneous quantification of T1 and T2 at 0.55T in a single cardiac-MRF scan of 16s could provide an alternative to higher field scanners, allowing for a more accessible way to assess cardiovascular disease.

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Keywords