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Abstract #0654

Imaging transformer for MRI denoising with SNR unit training: enabling generalization across field-strengths, imaging contrasts, and anatomy

Hui Xue1, Sarah Hooper1, Azaan Rehman1, Iain Pierce2, Thomas Treibel2, Rhodri Davies2, W Patricia Bandettini1, Rajiv Ramasawmy1, Ahsan Javed1, Yang Yang3, James Moon2, Adrienne Campbell-Washburn1, and Peter Kellman1
1National Heart, Lung, and Blood Institute, Bethesda, MD, United States, 2Barts Heart Centre at St. Bartholomew's Hospital, London, United Kingdom, 3University of California, San Francisco, San Francisco, CA, United States

Synopsis

Keywords: Other AI/ML, Machine Learning/Artificial Intelligence, imaging transformer, generalization

Motivation: MR denoising using the CNN models often requires abundant high quality data for training. In many applications, such as higher acceleration and low field, high quality data is not available. This study overcome this limitation by developing a SNR unit based training scheme and a novel imaging transformer (imformer) architecture.

Goal(s): To develop and validate a novel imformer model for MR denoising, enabling generalization across field-strengths, imaging contrasts, and anatomy.

Approach: SNR unit training scheme and imaging transformer architecture

Results: Imformer models outperformed CNNs and conventional transformer. The SNR training enables storng generalization.

Impact: Recovery high-fidelity MR signal from very low SNR inputs; Enable 0.55T MRI model training.

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Keywords